ABSTRACT Purpose: To evaluate gastrointestinal histological injury in pigs subjected to triple stent interposition versus a FIRM HOLD GEL control group, hypothesizing no significant injury increase with triple stents.Methods: A prospective study with 15 pigs divided into a control group (G0, n = 5) undergoing arteriography only, and a triple stent group (G3, n = 10) undergoing arteriography and three stent implantations in the thoracoabdominal aorta.After an eight-day observation, arteriography, euthanasia, and en bloc gastrointestinal harvesting were performed.Lesions were graded using the Park/Chiu classification, and serum markers were analyzed pre- and post-procedure.Results: Arteriography confirmed mesenteric artery patency in all animals.
Histological analysis showed ischemic lesions in 88.9% of G3, mainly in the colon (89%), compared vest to 60% in G0, primarily in the colon (60%) and stomach (40%).Most G3 lesions were grade 1, while G0 had higher-grade lesions.Serum markers showed no significant intergroup differences.Conclusion: Triple stent interposition did not significantly increase gastrointestinal injury, indicating its safety for maintaining gastrointestinal perfusion in this model.